Known in ancient times as “Palazzo delle pietre pizzute" (palace of the pointy stones), characterised by large diamond-point rustication that cover the upper floor, Palazzo de Mattis constitutes one of the most stunning examples of Renaissance architecture that sprung in Puglia after the grandiose Palazzo of the diamonds in Ferrara, attesting to the contacts that the latter had with Corato. Lucrezia Borgia, Duchess of Ferrara, administered the duchy of Corato and Bisceglie on behalf of her son Rodrigo from 1499 to 1513. The building was constructed in 1579 and belonged to the Patroni Griffi family as can be seen by the coat of arms that is displayed at the corner of the palazzo.